The bones have healed well but the plate is still in place. I have been wondering whether leaving the plate in my arm in the long term can cause side effects, because although I have been told that Titanium is inert in the body I have been getting strange itchy sensations on the back of my hands.
Have you come across any information on this subject? I wondered about this myself some years ago when I encountered a young lady who had recently had a Titanium plate inserted in her leg.
Very shortly afterward she became covered in psoriasis which previously she had not had. I have also seen referrals to studies that suggest that particulate tiny particles titanium may cause health problems either at the site overlying the implant or in more distant organs such as lungs and lymph nodes, particularly after some time of frictional wear. The only actual study I have come across that attempted to prove this was carried out on sheep poor things and reported in the Australian Dental Journal The conclusion of this report was that there was no significant release of Titanium particles in the short term but there were some longer term trends that indicated that there could be an increase of debris after longer periods, particularly in the lungs.
I have not seen any further reports of this type, most back up the theory that Titanium is inert in the body.
There are a number of reports of suspected reactions to Titanium contained in sunscreens, however these could well be reactions to other constituents of the sunscreen. I have also seen accumulations of Titanium in hair samples taken from people using either sunscreens or other skin products containing Titanium, but I guess this could be seen as an indication that the body rids itself of excess quite efficiently. All information on these pages has been compiled by Alison Odey from results seen and experienced in over 20 years in practice.
It is not intended to diagnose or to be construed as medical advice, but to inform the reader of alternative options that may be available to them. It is the responsibilty of the customer to inform their doctor about any of the products they intend to use. All Rights Reserved. Alison Odey. Titanium —? Disclaimer All information on these pages has been compiled by Alison Odey from results seen and experienced in over 20 years in practice.Password: Log In.
Lost your password? Fiona Randall answered on 18 Jun Joanna Brooks answered on 18 Jun This is a good question because there can be several side effects of having metal pins inside your body — but only if the pins have been inside your body for a very long period of time. But this would take a long time to happen.
The effects on bone cells of metal ions released from orthopaedic implants. A review
The main thing to remember is that doctors have very specialised knowledge about this and would not put someone at risk — technology and medicine have advanced so much over the past few decades and this procedure is probably safer than ever before. William Davies answered on 18 Jun Most implants these days are made from metal alloys mostly titanium that are extremely unreactive and hard-wearing.
I believe surgeons advise that things like artifical hips are replaced every years, but I think that is mainly precautionary and is not strictly necessary. Jane Henry answered on 18 Jun You can live with metal pins for ages because the metal used eg titanium, is designed not to react with other stuff in your body. I'm a Scientist: Supported by Wellcome.
Log in using the username and password we sent you Return visit? Meet the scientists! William Michelle Joanna Jane Fiona. Skip to content. Question : What are the side-effects of having metal pins inside your bone after a long-period of time? Joanna Brooks answered on 18 Jun Hello! Jane Henry answered on 18 Jun You can live with metal pins for ages because the metal used eg titanium, is designed not to react with other stuff in your body.Patients who have metal plates, pins, and screws in the body are rightfully concerned about the safety and long-term effects of these devices left inside.
Surgeons share those concerns but do not want to perform an additional surgery to remove them if unnecessary. And sometimes when plates are used to hold bone together after a fracture, bone grows around them embedding this fixation device too much to remove it easily. So just how s afe are these devices? In this article, Dr. David G. Dennison from the Orthopedic Surgery department of Mayo Clinic in Rochester, Minnesota summarizes what we know from research and clinical studies on this topic.
In particular, Dr. Dennison zeroes in on titanium volar plates used to treat distal radius fractures. Titanium has replaced stainless steel these days for fixation devices. Titanium can also be combined with other metals such as cobalt, chromium, and molybdenum to create a lighter but more durable material.
Volar plates refer to the location of fixation devices — placed on the front or inside of the forearm. Radius fracture tells us the radial bone in the forearm is broken. There are two bones in the forearm: ulna and radius.
The radius is on the thumb-side of the forearm.
Titanium Rejection Symptoms: Are You Allergic to Your Dental Implant?
Distal means the break is down toward the hand rather than up by the elbow. There are all kinds of concerns about metal plates. Animal studies show there is an effect on the immune system. There is evidence that the metal can cause the entire immune system to be suppressed under functioning.
This immune system shut down could result in infections. Some studies have shown that metal implants can cause an increase in white blood cells called lymphocyte reactivity. Another potential problem with titanium plates is the debris that occurs. Both titanium and stainless steel have been found in all these anatomical areas of the human body titanium slightly more often and in greater amounts than stainless steel.
Metal debris is more likely to develop when the implant is rubbing against another surface. This wearing or rubbing phenomenon is called fretting. Then the question arises: can this metal debris lead to the formation of cancer? Studies in mice show there is the potential for metal wear debris to damage chromosomes making it a potential carcinogen cancer producing.
Next, developers of these products asked if coating the plate would protect the body from corrosion or metal debris? This question remains unanswered so far. One thing we do know from studies — placing a long titanium or metal pin down through the middle of a bone to stabilize it is linked with a much higher increase in the amount of metal found in the bloodstream. Chromium seems to have the highest levels reported for these intramedullary nails. Intramedullary titanium nails also increase the amount of titanium found in blood samples, but not as much as chromium.
Evidently, the large surface area of the intramedullary nail exposes the bone to more titanium, thus the higher levels of serum blood metal.The increasing use of orthopedic implants and, in particular, of hip and knee joint replacements for young and active patients, has stimulated interest and concern regarding the chronic, long-term effects of the materials used.
This review focuses on the current knowledge of the adverse biologic reactions to metal particles released from orthopaedic implants in vivo and in vitro. More specifically, the purpose of this article is to provide an overview of the current literature about the adverse effects of metal particles on bone cells and peri-implant bone.
Over the last 30 years, orthopaedic surgery has immeasurably improved the lives of millions of people, restoring their mobility, bringing pain relief and ultimately giving them a better quality of life.
The main orthopaedic implants currently in use are prostheses for replacing arthritic joints, and devices for fixing fractures and stabilizing the spine. Joint replacement, and in particular knee and hip replacement, has arguably seen the greatest advances in terms of investment, research and clinical results.
Prosthetic joint replacement has proved to be a highly reliable treatment even in the long term 1. However, in spite of the success of this type of surgery, there still remains the need for further progress; average life-expectancy is rising which necessitates ever more long-lasting implants, and complications and adverse effects are not infrequent 1 and often require the substitution of the prosthesis.
Furthermore, it is generally accepted that within 15—20 years after surgery, aseptic loosening of the implants is almost inevitable. If infection is excluded, the most frequent complication associated with joint replacement is the deterioration of the prosthetic components and the resulting biological response of the body to the material released by the implant.
Thus the generation of wear debris and the subsequent tissue reaction to this debris, have a fundamental effect on the longevity of total joint arthroplasties. Although adverse reactions to implants are relatively rare, if we take into account the huge number of prostheses implanted to date and the hundreds of thousands of new prostheses implanted each year, the problem could potentially be huge.
The situation has become more urgent with the increasing number of reports of adverse effects related to metal ion release from certain types of hip prosthesis, in particular those which have direct contact between two metal joint components MoM: metal-on-metal.
As these prostheses have mechanical characteristics which are particularly attractive, they have been widely used over the last few years, particularly in younger patients. Whilst adverse reactions to metals have been studied for many years by pathologists, toxicologists, company doctors and dermatologists, research has begun relatively recently in Orthopaedics, and therefore the results are limited.
The toxicokinetics of small metal wear particles and associated corrosion products remain unclear, and data are particularly scarce regarding the effect of metal ions on bone cells and bone resorption osteolysis.
In light of this lack of data and the emerging problems in the field of orthopaedic implants, we have carried out a review of the literature on the adverse effects of metal ion release.
The purpose of this review is to provide a comprehensive update on the effects of metal ions on bone cells and bone resorption after a surgical orthopaedic implant. The principal characteristic required by biomaterials if they are to be used in orthopaedic surgery is that they are resistant to repeated mechanical stress.
Only metals, ceramics and polymers meet this fundamental requirement Table 1. Amongst the orthopaedic biomaterials currently in use, only metals provide a combination of additional advantages: high strength, ductility, tenacity, hardness, fracture toughness, corrosion resistance, formability and biocompatibility.
Although initial prosthetic designs used stainless steel, over the years the metal alloys developed in the aeronautical and naval industries were adopted for use in Orthopaedics. The three main metal alloys used in the production of joint prostheses are the following: stainless steel based alloys; cobalt alloys; and titanium alloys.
Each of these alloys has its own particular strength, rigidity and ductility properties. However, their high resistance to corrosion has made them particularly suitable for use in the manufacture of orthopaedic implants.We pride ourselves on being your source for the best, scientifically-accurate advice for healthy living.
This article contains references to scientific journals and peer-reviewed research. The numbers in brackets correspond with the list of references at the end of the article. Reviewed and Approved. Additionally, the Reviewed and Approved seal signifies that our scientific board of experts has double-checked this article for accuracy. You can feel confident in knowing that the information within this article is sound. Titanium is the ninth most abundant element in the Earth's crust.
This abundance and its status as a corrosion resistant, strong metal have landed it many industrial applications where its best features can be fully taken advantage of. Some uses include airplane motors, jewelry, and heat exchange systems. Because titanium itself is non-toxic and not rejected by the body, the medical industry has embraced it for implants such as hip and joint replacements.
Despite the upsides, much concern has been expressed about the use of titanium compounds as a food and cosmetic additive. Exposure to titanium often happens by way of titanium compounds that are added to cosmetics, sunscreens, paints, and food. Titanium dioxide nano particles is usually the compound in question and safety concerns have been expressed. Unfortunately, you don't have a choice in whether or not you're exposed.
Even if you avoid products that contain titanium dioxide nano particles, the other nano particles that everyone else uses will be excreted or washed away into the sewage system and into the environment. Even with a low exposure, this may manifest into a range of effects.
The Health Risks of Titanium
Another matter of concern is that titanium dioxide is an ingredient in food coloring A Monte Carlo analysis found that children have the greatest exposure because of high titanium content in sweets. Personal care products such as toothpastes and sunscreens often contain titanium too.
The safety profile of nano particles for infants and the unborn is not known. Some studies have suggested the concern over titanium nano particle safety to be "overblown". I disagree. Titanium oxide nano particles have been shown to induce emphysema and lung redness in adult mice.
Furthermore, exposure of developing lungs to nano particles may lead to chronic irritation and negative effect on lung development, increasing the risk of respiratory disorders. No thanks! Inhaling titanium nano particles is bad for your lungs. Researchers at the National Institute for Occupational Safety and Health in Morgantown West Virginia observed significantly elevated levels of lung injury in rats that had inhaled titanium compounds.
Titanium exposure may be harmful to your brain. Titanium nano particles can enter directly into the hippocampus region of the brain through the nose and olfactory bulb. Long-term chronic exposure and environmental pollution are not documented and a relationship between nano particle exposure and development of degenerative brain diseases may exist. The biggest kicker is that even though although titanium dioxide is permitted as an additive in food and pharmaceutical products, it's also classified as "possible carcinogenic to humans" by the International Agency for Research on Cancer and the National Institute for Occupational Safety and Health.
Studies show that titanium dioxide causes adverse effects by producing oxidative stress, resulting in cell damage, redness, and immune response.It is technically simple but has high complication rates. This study aimed to determine the incidence and predictors of complications following TC. Statistical analysis included correlation, independent variable analysis and descriptive methods.
The commonest complication was infection and the overall removal rate was 8. The mean cranioplasty area was There was no significant relationship between area and complications, removal rates or infections.
There was no relationship between age and total complications, post-operative hospital stay and infections.
Can Titanium Plates Be Left in the Body Safely?
There was a non-significant trend for older patients to have their cranioplasty removed. However, the TC size is not predictive of complications or removal rate.
Also, there was no association between interval since primary operation and complications. There was a non-significant trend for greater rates of TC removal in the elderly. There were no predictors of complications identified but they are common and patients should be consented accordingly.FAQ on Coronavirus and Mefi : check before posting, cite sources; how to block content by tags. Allergic reaction to metal esp titanium surgically inserted plate? I've been experiencing symptoms that include episodes of extreme fatigue, as well as sore throat and general sick feeling for the past 6 months or so.
Before that I would experience this sick feeling minimally starting shortly after the plate was surgically implanted in my arm. The plate is now useless and can be removed, I was wondering if anyone had ever experienced a similar reaction? Thanks for any help! Desperately trying to get to the bottom of this mystery!
Yes, but I'd get an allergy test firstas it's less invasive, I think? Wow that's crazy I had a titanium implanted for a bad fracture of my humerus in March of Mine just hurts all the time.High Tibial Osteotomy (HTO) for Bow Leg Correction
The bone has healed and it just adds strength I guess. Hope I don't develop an allergy to the titanium.
Will be following this post to keep up with you on it. Since I am not a doctor, I will simply summarize my unqualified understanding of titanium implants I have one as well. There are many web pages to look for under this subject; I am deliberately not linking you to any of them as I am not qualified to indicate which ones are more or less accurate.
As I understand, titanium allergies are incredibly rare, but not non-existent. Most surgeons are both generally unwilling to entertain the possibility of an allergy due to the rarity of the allergy and generally unwilling to preemptively remove an implant due to possibly performing unnecessary surgery.
However, similarly, most surgeons are willing to remove an implant after a certain amount of time if it really bothers you - for instance, my surgeon offered to remove it after a year. This is a reasonable question to ask your surgeon, but be prepared to be faced with skepticism. Neither a medical professional, nor taking any related courses any longer, but during a bio course a few years ago, I had the opportunity to tour the Center for Genomic Sciences at AGH here in Pittsburgh, during which time we were able to view imaging of mostly staph biofilms growing on, among other things, titanium implants despite improvement in antimicrobial coatings.
I'm just going to tell you what happened to me. I smashed my femur in a MC accident.